Compounded Tirzepatide + Glycine Injections
Price range: $199.00 through $449.00
Initial charge of $34 for consult, price of medication(s) charged upon consult approval.
Dual-action GLP-1/GIP therapy paired with glycine to support metabolic health, weight management, and overall wellness—personalized to your goals and guided by a licensed provider.
Compounded tirzepatide with glycine is a prescription medication designed to support weight management and metabolic health through dual incretin activity—GLP-1 and GIP receptor agonism—combined with the amino acid glycine.
Tirzepatide works on key metabolic hormones that help regulate appetite, blood sugar, and energy balance. Glycine is a naturally occurring amino acid that supports metabolic processes, tissue repair, and overall wellness. Together, they are used as part of a comprehensive, clinician-directed approach that pairs medication with nutrition, movement, sleep, and lifestyle changes.
This once-weekly, at-home injectable is personalized to your health profile—not a one-size-fits-all “quick fix.”
Important Note: Compounded medications are prepared by licensed U.S. compounding pharmacies and are not reviewed or approved by the FDA. Your Wellcore provider will determine if compounded tirzepatide with glycine is appropriate based on your clinical evaluation.
This therapy leverages dual incretin signaling plus amino-acid support:
Tirzepatide (GLP-1/GIP receptor agonist):
- Activates GLP-1 receptors to help regulate appetite, reduce cravings, and slow gastric emptying
- Activates GIP receptors, which further support insulin response and metabolic efficiency
- Helps you feel fuller sooner and stay satisfied longer to support sustainable calorie reduction
- Supports blood-sugar regulation and overall metabolic balance
Glycine (amino acid):
- Supports healthy metabolic and cellular processes
- Plays a role in tissue repair, muscle recovery, and collagen synthesis
- Helps support restorative sleep and overall well-being when combined with healthy lifestyle habits
Together, tirzepatide and glycine are designed to support weight management, metabolic health, and general wellness within a structured, clinician-guided plan.
Compounded tirzepatide with glycine offers a flexible, integrated metabolic solution:
- Dual-pathway incretin support – Targets both GLP-1 and GIP receptors for broader metabolic impact
- GLP-1 + amino-acid pairing – Combines tirzepatide with glycine to support whole-body wellness and recovery
- Once-weekly, at-home injections – Subcutaneous injections you administer yourself; no routine office visits required
- Clinician-guided dosing and titration – Personalized starting dose and escalation plan based on your response
- Flexible vial strengths – Compounded in a range of vial sizes to align with your treatment stage and goals
- Prepared by licensed U.S. compounding pharmacies – With ongoing oversight from your Wellcore provider
- Integrated into a real-world lifestyle – Designed to work alongside nutrition, movement, sleep, and stress-management—not replace them
Use this general guide to understand potential eligibility. Final eligibility is always determined by a Wellcore provider after a full evaluation.
| BMI | Am I Eligible?* |
| ≤ 24.9 | Not eligible |
| 25.0–26.9 | Case-by-case** |
| 27.0–29.9 | Likely eligible** |
| 30.0+ | Likely eligible** |
Compounded tirzepatide with glycine may be considered for adults who:
- Are seeking medical support for weight management and metabolic health
- Have struggled to achieve or maintain weight-loss goals with lifestyle changes alone
- Prefer a dual-action incretin option with once-weekly dosing
- Are ready to pair medication with ongoing lifestyle optimization
- Do not have medical conditions that make GLP-1/GIP therapy unsafe
Your provider will also consider factors such as insulin resistance, prediabetes or diabetes, cardiovascular risk, GI history, and current medications before recommending this therapy.
Your provider will create a dosing and titration plan tailored to you.
General guidance includes:
- Route: Subcutaneous injection (just under the skin), typically in the abdomen or thigh
- Frequency: Inject once weekly, on the same day each week, as directed
- Titration: You will usually start on a lower dose and increase gradually to help minimize side effects
- Consistency: Take your dose at roughly the same time each week for steady exposure
- Instructions: Each shipment includes step-by-step instructions for storage, preparation, and self-injection
Never change your dose, skip titration steps, or alter your schedule without consulting your provider.
Complete Treatment Package
- Multi-dose vial(s) of compounded tirzepatide with glycine in your prescribed strength
- Syringes, injection needles, and alcohol swabs
- Provider-directed dosing and titration instructions
- Cold-packed, discreet shipping delivered to your home (where permitted)
- Access to Wellcore’s clinical support team for questions, check-ins, and side-effect guidance
Kit components may vary slightly based on your prescription and partner pharmacy.
Your Treatment Journey
Start Your Online Evaluation
Get approved by provider
Receive Your product at Home
Start treatment with provider guidance
How is tirzepatide with glycine different from tirzepatide with B12?
Both are tirzepatide-based therapies that support weight management and metabolic health through GLP-1 and GIP receptor activation. In one formulation, tirzepatide is paired with B12, primarily to support cellular energy and red blood cell health. In this formulation, tirzepatide is paired with glycine, an amino acid that supports tissue repair, recovery, and overall wellness. Your provider can help decide which pairing best aligns with your health status and goals.
Is compounded tirzepatide with glycine FDA-approved?
No. Compounded tirzepatide with glycine is not reviewed or approved by the FDA. It is prepared for individual patients by licensed U.S. 503A compounding pharmacies under a provider’s prescription. Your Wellcore provider will explain how compounded therapy compares to FDA-approved options and whether it’s appropriate for you.
How soon will I notice changes?
Experiences vary. Many people notice changes in appetite, fullness, and cravings within the first several weeks. Changes in weight and body composition typically develop over 1–3+ months depending on your baseline, dose, adherence, and lifestyle habits. Your provider will monitor your progress and adjust your dosing plan as needed.
Do I still need to focus on diet, movement, and sleep?
Yes. Compounded tirzepatide with glycine is designed to enhance healthy lifestyle habits—not replace them. Sustainable results come from combining medication with balanced nutrition, consistent movement, quality sleep, and effective stress management.
Can I switch between GLP-1/GIP medications later?
Potentially. If your needs change, your provider may consider transitioning you between GLP-1/GIP therapies or to a different incretin option. Any change in therapy should be planned and supervised by your provider. Do not stop, start, or switch medications on your own.
Do Not Use This Medication If You:
- Have a personal or family history of medullary thyroid carcinoma (MTC)
- Have multiple endocrine neoplasia syndrome type 2 (MEN 2)
- Are pregnant, planning to become pregnant, or breastfeeding
- Are allergic to tirzepatide, glycine, or any ingredient in the formulation
Use With Caution If You:
- Have a history of pancreatitis
- Have severe gastrointestinal disease, such as gastroparesis
- Have significant kidney or liver impairment
- Take medications that affect blood sugar, insulin, or gastric emptying
- Have complex cardiovascular or endocrine conditions
Always provide your provider with a complete list of medications, supplements, and medical conditions before starting therapy.
Common Side Effects May Include:
- Nausea (especially during dose escalation)
- Bloating, fullness, or mild stomach discomfort
- Constipation or diarrhea
- Decreased appetite
- Headache or fatigue
- Mild redness, itching, or discomfort at the injection site
Side effects are often mild to moderate and may improve as your body adjusts and as your provider gradually increases your dose. Contact your provider if symptoms are severe, persistent, or concerning.
Seek immediate medical attention if you experience signs of a severe allergic reaction (hives, swelling of the face, lips, tongue, or throat, difficulty breathing), severe abdominal pain, or other alarming symptoms.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. The information provided here is for educational purposes only and does not replace individualized medical advice from a qualified healthcare professional.
Important Information About Compounded Tirzepatide with Glycine
- Compounded medications are not reviewed or approved by the FDA and do not undergo the same pre-market testing as FDA-approved drugs.
- Wellcore’s compounded tirzepatide with glycine is prepared using tirzepatide base and glycine by FDA-registered, U.S.-licensed 503A compounding pharmacies, where available and appropriate.
- Product availability may vary based on state regulations, clinical appropriateness, and pharmacy partners.
Wellcore does not practice medicine or provide direct medical care. All prescriptions and treatment decisions are made independently by licensed healthcare providers exercising their professional judgment. Images and product representations are for illustration only; actual packaging and supplies may differ.
*If you are interested in a prescription product, Wellcore will coordinate a telehealth consultation with a licensed medical provider who will evaluate whether you are an appropriate candidate based on your health profile and current standards of care. If approved, your prescription will be filled by one of our partner pharmacies unless you request a different pharmacy. All prescriptions are subject to provider discretion and clinical appropriateness.